Factors Participating in the Occurrence of Inflammation of the Lips (Cheilitis) and Perioral Skin

Lip inflammation may manifest as mainly reversible cheilitis, irreversible, or cheilitis connected to dermatoses systemic diseases. Therefore, knowing a patient’s medical history is important, especially whether their lip lesions are temporary, recurrent, persistent. Sometimes temporary contributing factors, such climate and weather conditions, can be identified avoided—exposure extreme conditions (e.g., dry, hot, windy climates) cause trigger inflammation. Emotional psychological stress also mentioned in the etiology of some inflammations exfoliative cheilitis) associated with nervous habits licking. To better manage it helpful look for potential concomitant comorbidities presence related diseases/conditions. Some forms accompany dermatologic diseases (lichen, pemphigus pemphigoid, erythema multiforme, lupus, angioedema, xerostomia, etc.) that should uncovered. Occasionally, persistent involve histological changes: actinic granulomatous glandular plasmacellular cheilitis. Perioral skin simultaneous perioral dermatitis have various causes: use corticosteroids cosmetics, dysfunction skin’s epidermal barrier, contact reaction allergens irritants toothpaste, dental fillings), microorganisms Demodex spp., Candida albicans, fusiform bacteria), hormonal changes, an atopic predisposition. Epidermal barrier worsen secondary vitamin mineral deficiencies zinc deficiency), occlusive emollient use, sunscreen excessive exposure environmental factors heat, wind, ultraviolet light. Current trends research uncovering valuable information concerning microbiome disruption persons suffering from dermatitis. Ultimately, effective approach patient management must take all these new into account.